Cell Culture Engineering

  1. N. Templeton, K. D. Smith, A. G. McAtee-Pereira, H. Dorai, M. J. Betenbaugh, S. E. Lang, J. D. Young. Application of 13C flux analysis to identify high-productivity CHO metabolic phenotypes. Metabolic Engineering, accepted. [Link to article]
  2. Junker, Beth H., and Jamey D. Young. Editorial overview: pharmaceutical biotechnology: engineering cells for high quality biopharmaceuticals production. Current opinion in biotechnology 30: viii. 2014. [Link to article]
  3. J.D. Young. 13C metabolic flux analysis of recombinant expression hosts. Current Opinion in Biotechnology 30:238-245, 2014.  [Link to article]
  4. N. Templeton, A. Lewis, H. Dorai, E.A. Qian, M.P. Campbell, K.D. Smith, S.E. Lang, M.J. Betenbaugh, J.D. Young. The impact of anti-apoptotic gene Bcl-2? expression on CHO central metabolism. Metabolic Engineering 25:92-102, 2014.  [Link to article]
  5. A.G. McAtee, N. Templeton, J.D. Young. Role of Chinese hamster ovary central carbon metabolism in controlling the quality of secreted biotherapeutic proteins. Pharmaceutical Bioprocessing 2:63-74, 2014.  [Link to article]
  6. J. D. Young. Metabolic flux rewiring in mammalian cell cultures. Current Opinion in Biotechnology 24:1108–1115, 2013. [Link to article]
  7. N. Templeton, J. Dean, P. Reddy, J. D. Young. Peak antibody production is associated with increased oxidative metabolism in an industrially relevant fed-batch CHO cell culture. Biotechnology and Bioengineering 110:2013–2024, 2013.  [Link to article]