Metabolic Flux Analysis

  1. Cheah, Yi Ern, Clinton M. Hasenour, and Jamey D. Young. "13C Flux Analysis in Biotechnology and Medicine." Systems Biology 6:25, 2017. [Link to article]
  2. D. McCloskey, J. D. Young, S. Xu, B. O. Palsson, A. M. Feist. Modeling method for increased precision and scope of directly measurable fluxes at a genome-scale. Analytical Chemistry 88:3844-52, 2016. [Link to article]
  3. D. McCloskey, J. D. Young, S. Xu, B. O. Palsson, A. M. Feist. MID Max: LC-MS/MS method for measuring the precursor and product mass isotopomer distributions of metabolic intermediates and cofactors for metabolic flux analysis applications. Analytical Chemistry 88:1362-1370, 2016. [Link to article]
  4. A.G. McAtee, L.J. Jazmin, J.D. Young. Application of isotope labeling experiments and 13C flux analysis to enable rational pathway engineering. Current Opinion in Biotechnology, 36:50-56, 2015.  [Link to article]
  5. J.M. Buescher, M.R. Antoniewicz, LG. Boros, S.C. Burgess, H. Brunengraber, C.B. Clish, R.J. DeBerardinis, O. Feron, C. Frezza, B. Ghesquiere, E. Gottlieb, K. Hiller, R.G. Jones, J.J. Kamphorst, R.G. Kibbey, A.C. Kimmelman, J.W. Locasale, S.Y. Lunt, O.D.K. Maddocks, C. Malloy, C.M. Metallo, E.J. Meuillet, J. Munger, K. Noh, J.D. Rabinowitz, M. Ralser, U. Sauer, G. Stephanopoulos, J. St-Pierre, D.A. Tennant, C. Wittmann, M.G. Vander Heiden, A. Vazquez, K. Vousden, J.D. Young, N. Zamboni, S. Fendt. A roadmap for interpreting 13C metabolite labeling patterns from cells. 34:189-201, 2015. [Link to article]
  6. J.D. Young. INCA: A computational platform for isotopically nonstationary metabolic flux anlaysis. Bioinformatics 30:1333-1335, 2014.  [Link to article]
  7. J.D. Young, D.K. Allen, J.A. Morgan. Isotopmer measurement techniques in metabolic flux analysis II: Mass spectrometry. Methods in Molecular Biology 1083:85-108, 2014.  [Link to article]
  8. T. A. Murphy, J. D. Young. ETA: Robust software for determination of cell specific rates from extracellular time courses. Biotechnology and Bioengineering 110:1748–1758, 2013.  [Link to article]
  9. L. J. Jazmin, J. D. Young. Isotopically nonstationary 13C metabolic flux analysis. Methods in Molecular Biology 985:367–390, 2013. [Link to article]
  10. O. Srour, J. D. Young, Y. C. Eldar. Fluxomers – A new approach for 13C metabolic flux analysis. BMC Systems Biology 5:129, 2011.  [Link to article]
  11. J. L. Reed, R. S. Senger, M. R. Antoniewicz, J. D. Young. Computational approaches in metabolic engineering. Journal of Biomedicine and Biotechnology 2010:207414, 2010.  [Link to article]
  12. J. D. Young1, J. L. Walther1, M. R. Antoniewicz, H. Yoo, G. Stephanopoulos. An elementary metabolite unit (EMU) based method of isotopically nonstationary flux analysis. Biotechnology and Bioengineering 99: 686–99, 2008.  [Link to article]

1Equal contributions.